Structure of PDB 2b1z Chain A Binding Site BS01

Receptor Information
>2b1z Chain A (length=235) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2b1z Molecular characterization of a B-ring unsaturated estrogen: implications for conjugated equine estrogen components of premarin.
Resolution1.78 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 D538 L539 E542 M543
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 E76 D225 L226 E229 M230
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2b1z, PDBe:2b1z, PDBj:2b1z
PDBsum2b1z
PubMed17949766
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

[Back to BioLiP]