Structure of PDB 2b1o Chain A Binding Site BS01

Receptor Information
>2b1o Chain A (length=212) Species: 44689 (Dictyostelium discoideum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVDANKVKFFFGKNCTGESFEYNKGETVRFNNGDKWNDKFMSCLVGSNVR
CNIWEHNEIDTPTPGKFQELAQGSTNNDLTSINGLSKFQVLPGAFQWAVD
VKIVNKVNSTAGSYEMTITPYQVDKVACKDGDDFVQLPIPKLTPPDSEIV
SHLTVRQTHTPYDYVVNGSVYFKYSPTTGQVTVIKKDETFPKNMTVTQDD
NTSFIFNLNSEK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2b1o Chain A Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2b1o Solution structures of the adhesion molecule DdCAD-1 reveal new insights into Ca(2+)-dependent cell-cell adhesion
ResolutionN/A
Binding residue
(original residue number in PDB)		D39 F41 T81 N84
Binding residue
(residue number reindexed from 1)		D38 F40 T80 N83
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0042802 identical protein binding
Biological Process
GO:0007155 cell adhesion
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0010468 regulation of gene expression
GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0030587 sorocarp development
GO:0031152 aggregation involved in sorocarp development
GO:0031288 sorocarp morphogenesis
GO:0050829 defense response to Gram-negative bacterium
GO:0051702 biological process involved in interaction with symbiont
GO:0098609 cell-cell adhesion
GO:1904643 response to curcumin
Cellular Component
GO:0000331 contractile vacuole
GO:0001726 ruffle
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005811 lipid droplet
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005938 cell cortex
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0030027 lamellipodium
GO:0030139 endocytic vesicle
GO:0030175 filopodium
GO:0031012 extracellular matrix
GO:0045335 phagocytic vesicle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2b1o, PDBe:2b1o, PDBj:2b1o
PDBsum2b1o
PubMed17057715
UniProtP54657|CAD1_DICDI Calcium-dependent cell adhesion molecule 1 (Gene Name=cadA)

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