Structure of PDB 2b0f Chain A Binding Site BS01

Receptor Information
>2b0f Chain A (length=182) Species: 12131 (rhinovirus B14) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPNTEFALSLLRKNIMTITTSKGEFTGLGIHDRVCVIPTHAQPGDDVLVN
GQKIRVKDKYKLVDPENINLELTVLTLDRNEKFRDIRGFISEDLEGVDAT
LVVHSNNFTNTILEVGPVTMAGLINLSSTPTNRMIRYDYATKTGQCGGVL
CATGKIFGIHVGGNGRQGFSAQLKKQYFVEKQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2b0f NMR solution structures of the apo and peptide-inhibited human rhinovirus 3C protease (Serotype 14): structural and dynamic comparison
ResolutionN/A
Binding residue
(original residue number in PDB)		K22 H40 E71 I124 N125 L126 S127 S128 K142 T143 G144 C146 H160 V161 G162 G163 N164 F169
Binding residue
(residue number reindexed from 1)		K22 H40 E71 I124 N125 L126 S127 S128 K142 T143 G144 C146 H160 V161 G162 G163 N164 F169
Enzymatic activity
Catalytic site (original residue number in PDB) H40 E71 G144 C146
Catalytic site (residue number reindexed from 1) H40 E71 G144 C146
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2b0f, PDBe:2b0f, PDBj:2b0f
PDBsum2b0f
PubMed17944485
UniProtP03303|POLG_HRV14 Genome polyprotein

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