Structure of PDB 2azm Chain A Binding Site BS01
Receptor Information
>2azm Chain A (length=193) Species:
9606
(Homo sapiens) [
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TAPKVLFTGVVDARGERAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCA
LGRGIPILSLDWLHQSRKAGFFLPPDEYVVTDPEQEKNFGFSLQDALSRA
RERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVI
TCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEAFVLSP
Ligand information
>2azm Chain C (length=5) Species:
9606
(Homo sapiens) [
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ASQEY
Receptor-Ligand Complex Structure
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PDB
2azm
MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks
Resolution
2.41 Å
Binding residue
(original residue number in PDB)
T1898 G1899 R1932 R1933 T1934 K1936 P2009
Binding residue
(residue number reindexed from 1)
T8 G9 R42 R43 T44 K46 P119
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2azm
,
PDBe:2azm
,
PDBj:2azm
PDBsum
2azm
PubMed
16377563
UniProt
Q14676
|MDC1_HUMAN Mediator of DNA damage checkpoint protein 1 (Gene Name=MDC1)
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