Structure of PDB 2axf Chain A Binding Site BS01

Receptor Information
>2axf Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAP
WIEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYG
CDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQRRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>2axf Chain C (length=10) Species: 10377 (Human herpesvirus 4 strain B95-8) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
APQPAPENAY
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2axf The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation
Resolution1.8 Å
Binding residue
(original residue number in PDB)
Y7 N63 N70 Y74 E76 S77 N80 Y84 R97 Y99 S116 T143 K146 W147 R156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 N63 N70 Y74 E76 S77 N80 Y84 R97 Y99 S116 T143 K146 W147 R156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2axf, PDBe:2axf, PDBj:2axf
PDBsum2axf
PubMed16275762
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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