Structure of PDB 2av7 Chain A Binding Site BS01

Receptor Information
>2av7 Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRAVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>2av7 Chain C (length=9) Species: 11927 (Human T-cell lymphotrophic virus type 1 (Caribbean isolate)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LLFGYPVYV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2av7 Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants.
Resolution2.05 Å
Binding residue
(original residue number in PDB)		Y7 E63 V67 T73 V76 D77 Y84 R97 Y99 T143 K146 W147 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 E63 V67 T73 V76 D77 Y84 R97 Y99 T143 K146 W147 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2av7, PDBe:2av7, PDBj:2av7
PDBsum2av7
PubMed16197958
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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