Structure of PDB 2as9 Chain A Binding Site BS01

Receptor Information
>2as9 Chain A (length=207) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEKNVTQVKDTNNFPYNGVVSFKDATGFVIGKNTIITNKHVSKDYKVGDR
ITAHPNGDKGNGGIYKIKSISDYPGDEDISVMNIEEQAVERGPKGFNFNE
NVQAFNFAKDAKVDDKIKVIGYPLPAQNSFKQFESTGTIKRIKDNILNFD
AYIEPGNSGSPVLNSNNEVIGVVYGGIGKIGSEYNGAVYFTPQIKDFIQK
HIEQHHH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2as9 Chain A Residue 333 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2as9 Functional and Structural Characterization of Spl Proteases from Staphylococcus aureus
Resolution1.7 Å
Binding residue
(original residue number in PDB)		H205 H207
Binding residue
(residue number reindexed from 1)		H205 H207
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.-
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2as9, PDBe:2as9, PDBj:2as9
PDBsum2as9
PubMed16516230
UniProtQ2FXC4|SPLC_STAA8 Serine protease SplC (Gene Name=splC)

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