Structure of PDB 2ao6 Chain A Binding Site BS01
Receptor Information
>2ao6 Chain A (length=242) Species:
9606
(Homo sapiens) [
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PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIATSCSRRFYQLTKLLDSVQPIARELHQF
TFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
Ligand information
>2ao6 Chain B (length=11) Species:
9606
(Homo sapiens) [
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GNAALRYLLGA
Receptor-Ligand Complex Structure
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PDB
2ao6
Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance
Resolution
1.89 Å
Binding residue
(original residue number in PDB)
V716 K720 R726 V730 M734 Q738 M894 E897
Binding residue
(residue number reindexed from 1)
V46 K50 R56 V60 M64 Q68 M218 E221
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2ao6
,
PDBe:2ao6
,
PDBj:2ao6
PDBsum
2ao6
PubMed
15525515
UniProt
P10275
|ANDR_HUMAN Androgen receptor (Gene Name=AR)
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