Structure of PDB 2a83 Chain A Binding Site BS01

Receptor Information
>2a83 Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDAASPREEPRAP
WIEQEGPEYWDRETQICKAKAQTDREDLRTLLRYYNQSEAGSHTLQNMYG
CDVGPDGRLLRGYHQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2a83 Conformational dimorphism of self-peptides and molecular mimicry in a disease-associated HLA-B27 subtype.
Resolution1.4 Å
Binding residue
(original residue number in PDB)
Y7 H9 T24 E45 R62 E63 Q65 I66 C67 K70 T73 E76 D77 Y84 Y99 T143 K146 W147 V152 L156 Y159 E163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 H9 T24 E45 R62 E63 Q65 I66 C67 K70 T73 E76 D77 Y84 Y99 T143 K146 W147 V152 L156 Y159 E163 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2a83, PDBe:2a83, PDBj:2a83
PDBsum2a83
PubMed16221670
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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