Structure of PDB 2a5c Chain A Binding Site BS01

Receptor Information
>2a5c Chain A (length=123) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARKCSLTGKWTNDLGSNMTIGAVNSRGEFTGTYTTAVTATSNEIKESPLH
GTENTINKRTQPTFGFTVNWKFSESTTVFTGQCFIDRNGKEVLKTMWLLR
SSVNDIGDDWKATRVGINIFTRL
Ligand information
Ligand ID8DA
InChIInChI=1S/C10H15N5O4/c11-8-7-9(13-3-12-8)15(10(18)14-7)6-1-4(17)5(2-16)19-6/h4-6,12,16-17H,1-3,11H2,(H,14,18)/t4-,5+,6+/m1/s1
InChIKeyKTCVXRUKSBTHOG-SRQIZXRXSA-N
SMILES
SoftwareSMILES
CACTVS 3.341NC1=C2NC(=O)N([C@@H]3C[C@@H](O)[C@H](CO)O3)C2=NCN1
OpenEye OEToolkits 1.5.0C1C(C(OC1N2C3=NCNC(=C3NC2=O)N)CO)O
OpenEye OEToolkits 1.5.0C1[C@H]([C@@H](O[C@@H]1N2C3=NCNC(=C3NC2=O)N)CO)O
CACTVS 3.341NC1=C2NC(=O)N([CH]3C[CH](O)[CH](CO)O3)C2=NCN1
ACDLabs 10.04O=C2NC1=C(N)NCN=C1N2C3OC(C(O)C3)CO
FormulaC10 H15 N5 O4
Name8-OXODEOXYADENOSINE
ChEMBL
DrugBank
ZINCZINC000103530118
PDB chain2a5c Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2a5c Recognition of oxidatively modified bases within the biotin-binding site of avidin.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		L14 W70 T77 N118
Binding residue
(residue number reindexed from 1)		L14 W70 T77 N118
Annotation score1
Binding affinityMOAD: Kd=24uM
PDBbind-CN: -logKd/Ki=4.62,Kd=24uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0019731 antibacterial humoral response
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:2a5c, PDBe:2a5c, PDBj:2a5c
PDBsum2a5c
PubMed16413579
UniProtP02701|AVID_CHICK Avidin (Gene Name=AVD)

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