Structure of PDB 2a3l Chain A Binding Site BS01

Receptor Information
>2a3l Chain A (length=616) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QPDPIAADILRKEPEQETFVRLNVPLEVPTSDEVEAYKCLQECLELRKRY
VFQETVAPWEKEEPFAHYPQGKSDHCFEMQDGVVHVFANKDAKEDLFPVA
DATAFFTDLHHVLKVIAAGNIRTLCHRRLVLLEQKFNLHLMLNADKEFLA
QKSAPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRD
GTYLTLREVFESLDLTGYDLNVDLLDVHADKSTFHRFDKFNLKYNPCGQS
RLREIFLKQDNLIQGRFLGEITKQVFSDLEASKYQMAEYRISIYGRKMSE
WDQLASWIVNNDLYSENVVWLIQLPRLYNIYKDMGIVTSFQNILDNIFIP
LFEATVDPDSHPQLHVFLKQVVGFDLVDDESKPERRPTKHMPTPAQWTNA
FNPAFSYYVYYCYANLYVLNKLRESKGMTTITLRPHSGEAGDIDHLAATF
LTCHSIAHGINLRKSPVLQYLYYLAQIGLAMSPLSNNSLFLDYHRNPFPV
FFLRGLNVSLSTDDPLQIHLTKEPLVEEYSIAASVWKLSACDLCEIARNS
VYQSGFSHALKSHWIGKDYYKRGPDGNDIHKTNVPHIRVEFRDTIWKEEM
QQVYLGKAVISDEVVP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2a3l Chain A Residue 840 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2a3l Membrane association, mechanism of action, and structure of Arabidopsis embryonic factor 1 (FAC1).
Resolution3.34 Å
Binding residue
(original residue number in PDB)		H391 H393 H659 D736
Binding residue
(residue number reindexed from 1)		H168 H170 H436 D513
Annotation score1
Enzymatic activity
Enzyme Commision number 3.5.4.6: AMP deaminase.
Gene Ontology
Molecular Function
GO:0003876 AMP deaminase activity
GO:0019239 deaminase activity
Biological Process
GO:0009168 purine ribonucleoside monophosphate biosynthetic process
GO:0032264 IMP salvage

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2a3l, PDBe:2a3l, PDBj:2a3l
PDBsum2a3l
PubMed16543243
UniProtO80452|AMPD_ARATH AMP deaminase (Gene Name=AMPD)

[Back to BioLiP]