Structure of PDB 2a3i Chain A Binding Site BS01
Receptor Information
>2a3i Chain A (length=253) Species:
9606
(Homo sapiens) [
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RALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVV
KWAKVLPGFKNLPLEDQITLIQYSWMSLSSFALSWRSYKHTNSQFLYFAP
DLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTI
PKDGLKSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSM
HDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYF
HRK
Ligand information
>2a3i Chain B (length=12) Species:
9606
(Homo sapiens) [
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QQKSLLQQLLTE
Receptor-Ligand Complex Structure
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PDB
2a3i
Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor
Resolution
1.95 Å
Binding residue
(original residue number in PDB)
V781 K782 K785 L795 I799 M959 E962
Binding residue
(residue number reindexed from 1)
V50 K51 K54 L64 I68 M228 E231
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2a3i
,
PDBe:2a3i
,
PDBj:2a3i
PDBsum
2a3i
PubMed
16061183
UniProt
P08235
|MCR_HUMAN Mineralocorticoid receptor (Gene Name=NR3C2)
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