Structure of PDB 1zzn Chain A Binding Site BS01

Receptor Information
>1zzn Chain A (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PETRPNHTIYINNLNEKIKKDELKKSLHAIFSRFGQILDILVSRSLKMRG
QAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMK
Ligand information
>1zzn Chain B (length=197) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggccgugugccuugcgccgggaaaccacgcaagggauggugucaaauucg
gcgaaaccuaagcgcccgcccgggcguauggcaacgccgagccaagcuuc
gcagccauugcacuccggcugcgaugaagguguagagacuagacggcacc
caccuaaggcaaacgcuauggugaaggcauaguccagggaguggcga
.........<<<<<<<..<<....>>.>>>>>>>...<<<<<<....<<<
<<<...<<...<<<<<<....>>>>>>..>>...>>>>>><<<.....<<
<<<<<<..........>>>>>>>>....>>>.....(((((...>>>>>>
<<<<...<<<....>>>..>>>>......))))).............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1zzn Structural evidence for a two-metal-ion mechanism of group I intron splicing.
Resolution3.37 Å
Binding residue
(original residue number in PDB)
Y13 N16 E19 S48 L49 K50 M51 R52 Q54 F56 Y86 A87 K88 T89 S91 D92
Binding residue
(residue number reindexed from 1)
Y10 N13 E16 S45 L46 K47 M48 R49 Q51 F53 Y83 A84 K85 T86 S88 D89
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:1zzn, PDBe:1zzn, PDBj:1zzn
PDBsum1zzn
PubMed16141079
UniProtP09012|SNRPA_HUMAN U1 small nuclear ribonucleoprotein A (Gene Name=SNRPA)

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