Structure of PDB 1zpu Chain A Binding Site BS01

Receptor Information
>1zpu Chain A (length=529) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ETHTFNWTTGWDYRNVDGLKSRPVITCNGQFPWPDITVNKGDRVQIYLTN
GMNNTNTSMHFHGLFQNGTASMDGVPFLTQCPIAPGSTMLYNFTVDYNVG
TYWYHSHTDGQYEDGMKGLFIIKDDSFPYDYDEELSLSLSEWYHDLVTDL
TKSFMSVYNPTGAEPIPQNLIVNNTMNLTWEVQPDTTYLLRIVNVGGFVS
QYFWIEDHEMTVVEIDGITTEKNVTDMLYITVAQRYTVLVHTKNDTDKNF
AIMQKFDDTMLDVIPSDLQLNATSYMVYNKTAALPTQNYVDSIDNFLDDF
YLQPYEKEAIYGEPDHVITVDVVMDNLKNGVNYAFFNNITYTAPKVPTLM
TVLSSGDQANNSEIYGSNTHTFILEKDEIVEIVLNNQDTGTHPFHLHGHA
FQTIQRDRTYDDALGEVPHSFDPDNHPAFPEYPMRRDTLYVRPQSNFVIR
FKADNPGVWFFHCHIEWHLLQGLGLVLVEDPFGIQDAHSQQLSENHLEVC
QSCSVATEGNAAANTLDLTDLTGENVQHA
Ligand information
Ligand IDMAN
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-PQMKYFCFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-mannopyranose;
alpha-D-mannose;
D-mannose;
mannose
ChEMBLCHEMBL365590
DrugBank
ZINCZINC000003860903
PDB chain1zpu Chain H Residue 5 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1zpu The copper-iron connection in biology: Structure of the metallo-oxidase Fet3p.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		L40 Q189 N190 D288 Q290
Binding residue
(residue number reindexed from 1)		L19 Q168 N169 D267 Q269
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H81 H83 G84 Q87 H126 S127 H128 Q132 M137 H413 H416 H418 H483 C484 H485 I486 H489 L494
Catalytic site (residue number reindexed from 1) H60 H62 G63 Q66 H105 S106 H107 Q111 M116 H392 H395 H397 H462 C463 H464 I465 H468 L473
Enzyme Commision number 1.16.3.1: ferroxidase.
1.16.3.4: cuproxidase.
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
Biological Process
GO:0006811 monoatomic ion transport

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1zpu, PDBe:1zpu, PDBj:1zpu
PDBsum1zpu
PubMed16230618
UniProtP38993|FET3_YEAST Iron transport multicopper oxidase FET3 (Gene Name=FET3)

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