Structure of PDB 1zl1 Chain A Binding Site BS01
Receptor Information
>1zl1 Chain A (length=361) Species:
9940
(Ovis aries) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEW
NDVTLYDTLNTLKNRNPKLKTLLSVGGWNFGPERFSAIASKTQSRRTFIK
SVPPFLRTHGFDGLDLAWLYPGRRDKRHLTTLVKEMKAEFIREAQAGTEQ
LLLSAAVSAGKIAIDRGYDIAQISRHLDFISLLTYDFHGAWRQTVGHHSP
LFAGNEDASSRFSNADYAVSYMLRLGAPANKLVMGIPTFGRSFTLASSKT
DVGAPVSGPGVPGRFTKEKGILAYYEICDFLHGATTHRFRDQQVPYATKG
NQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLTFPL
TSAVKDVLAEV
Ligand information
>1zl1 Chain C (length=3) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
WHW
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
1zl1
Crystal structure of the complex of signalling protein from sheep (SPS-40) with a designed peptide Trp-His-Trp reveals significance of Asn79 and Trp191 in the complex formation
Resolution
3.5 Å
Binding residue
(original residue number in PDB)
N79 W191
Binding residue
(residue number reindexed from 1)
N79 W191
Enzymatic activity
Catalytic site (original residue number in PDB)
D115 A117 L119 Y185
Catalytic site (residue number reindexed from 1)
D115 A117 L119 Y185
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0008061
chitin binding
GO:0030246
carbohydrate binding
Biological Process
GO:0005975
carbohydrate metabolic process
GO:0006032
chitin catabolic process
GO:0006915
apoptotic process
GO:0006954
inflammatory response
GO:0007250
activation of NF-kappaB-inducing kinase activity
GO:0009612
response to mechanical stimulus
GO:0010800
positive regulation of peptidyl-threonine phosphorylation
GO:0030324
lung development
GO:0032757
positive regulation of interleukin-8 production
GO:0034612
response to tumor necrosis factor
GO:0045766
positive regulation of angiogenesis
GO:0051897
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO:0070374
positive regulation of ERK1 and ERK2 cascade
GO:0070555
response to interleukin-1
GO:0070741
response to interleukin-6
GO:0071356
cellular response to tumor necrosis factor
Cellular Component
GO:0005576
extracellular region
GO:0005615
extracellular space
GO:0005737
cytoplasm
GO:0005783
endoplasmic reticulum
GO:0048471
perinuclear region of cytoplasm
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:1zl1
,
PDBe:1zl1
,
PDBj:1zl1
PDBsum
1zl1
PubMed
UniProt
Q6TMG6
|CH3L1_SHEEP Chitinase-3-like protein 1 (Gene Name=CHI3L1)
[
Back to BioLiP
]