Structure of PDB 1zky Chain A Binding Site BS01
Receptor Information
>1zky Chain A (length=239) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTFLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
>1zky Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
1zky
Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.
Resolution
2.25 Å
Binding residue
(original residue number in PDB)
I358 L372 V376 L379 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I55 L69 V73 L76 E77 D228 L229 E232
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1zky
,
PDBe:1zky
,
PDBj:1zky
PDBsum
1zky
PubMed
16648639
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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