Structure of PDB 1zho Chain A Binding Site BS01

Receptor Information
>1zho Chain A (length=228) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKHGKRYRALLEKVDPNKIYTIDEAAHLVKELATAKFDETVEVHAKLGID
PRRSDQNVRGTVSLPHGLGKQVRVLAIAKGEKIKEAEEAGADYVGGEEII
QKILDGWMDFDAVVATPDVMGAVGSKLGRILGPRGLLPNPKAGTVGFNIG
EIIREIKAGRIEFRNDKTGAIHAPVGKASFPPEKLADNIRAFIRALEAHK
PEGAKGTFLRSVYVTTTMGPSVRINPHS
Ligand information
>1zho Chain B (length=38) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggagugaaggaggcuucggccgcgaaacuucacuccc
<<<<<<<<<<..<<<....>>>......>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB1zho New insights into the interaction of ribosomal protein L1 with RNA.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		P1 H3 K5 R6 Y7 A35 K36 F37 T40 E42 H44 K46 K70 P133 R134 D166 K167 T168 H172 P174 Y213 T217 M218 G219 P220 S221
Binding residue
(residue number reindexed from 1)		P1 H3 K5 R6 Y7 A35 K36 F37 T40 E42 H44 K46 K70 P133 R134 D166 K167 T168 H172 P174 Y213 T217 M218 G219 P220 S221
Binding affinityPDBbind-CN: Kd=16.5nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0006417 regulation of translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1zho, PDBe:1zho, PDBj:1zho
PDBsum1zho
PubMed16330048
UniProtP27150|RL1_THETH Large ribosomal subunit protein uL1 (Gene Name=rplA)

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