Structure of PDB 1zdy Chain A Binding Site BS01

Receptor Information
>1zdy Chain A (length=301) Species: 93372 (Streptomyces sp. CL190) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EAADVERVYAAMEEAAGLLGVACARDKIYPLLSTFQDTLVEGGSVVVFSM
ASGRHSTELDFSISVPTSHGDPYATVVEKGLFPATGHPVDDLLADTQKHL
PVSMFAIDGEVTGGFKKTYAFFPTDNMPGVAELSAIPSMPPAVAENAELF
ARYGLDKVQMTSMDYKKRQVNLYFSELSAQTLEAESVLALVRELGLHVPN
ELGLKFCKRSFSVYPTLNWETGKIDRLCFAVISNDPTLVPSSDEGDIEKF
HNYATKAPYAYVGEKRTLVYGLTLSPKEEYYKLGAYYHITDVQRGLLKAF
D
Ligand information
Ligand IDT3A
InChIInChI=1S/C7H17NO6S/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14/h8-11H,1-6H2,(H,12,13,14)
InChIKeyYNLCVAQJIKOXER-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CNC(CO)(CO)CO)CS(=O)(=O)O
CACTVS 3.341OCC(CO)(CO)NCCC[S](O)(=O)=O
ACDLabs 10.04O=S(=O)(O)CCCNC(CO)(CO)CO
FormulaC7 H17 N O6 S
NameN-(TRIS(HYDROXYMETHYL)METHYL)-3-AMINOPROPANESULFONIC ACID
ChEMBL
DrugBank
ZINCZINC000001611594
PDB chain1zdy Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1zdy Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products.
Resolution1.44 Å
Binding residue
(original residue number in PDB)		H57 D62 K169 R228 Y282
Binding residue
(residue number reindexed from 1)		H55 D60 K167 R226 Y280
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004659 prenyltransferase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1zdy, PDBe:1zdy, PDBj:1zdy
PDBsum1zdy
PubMed15959519
UniProtQ4R2T2

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