Structure of PDB 1zbl Chain A Binding Site BS01

Receptor Information
>1zbl Chain A (length=133) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEIIWESLSVDVGSQGNPGIVEYKGVDTKTGEVLFEREPIPIGTNNMGEF
LAIVHGLRYLKERNSRKPIYSDSQTAIKWVKDKKAKSTLVRNEETALIWK
LVDEAEEWLNTHTYETPILKWQTDKWGEIKANY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1zbl Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D71 G73 S74 Q75 G76 N105 E109 D132 Q134 K180 T183
Binding residue
(residue number reindexed from 1)		D11 G13 S14 Q15 G16 N45 E49 D72 Q74 K120 T123
Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:1zbl, PDBe:1zbl, PDBj:1zbl
PDBsum1zbl
PubMed15989951
UniProtQ9KEI9|RNH1_HALH5 Ribonuclease H (Gene Name=rnhA)

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