Structure of PDB 1zbi Chain A Binding Site BS01

Receptor Information
>1zbi Chain A (length=135) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIIWESLSVDVGSQGNPGIVEYKGVDTKTGEVLFEREPIPIGTNNMGEFL
AIVHGLRYLKERNSRKPIYSNSQTAIKWVKDKKAKSTLVRNEETALIWKL
VDEAEEWLNTHTYETPILKWQTDKWGEIKADYGRK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1zbi Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		D71 V72 G73 S74 Q75 G76 N77 N105 E109 N132 Q134 K180 T183
Binding residue
(residue number reindexed from 1)		D10 V11 G12 S13 Q14 G15 N16 N44 E48 N71 Q73 K119 T122
Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:1zbi, PDBe:1zbi, PDBj:1zbi
PDBsum1zbi
PubMed15989951
UniProtQ9KEI9|RNH1_HALH5 Ribonuclease H (Gene Name=rnhA)

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