Structure of PDB 1z3s Chain A Binding Site BS01

Receptor Information
>1z3s Chain A (length=216) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRRE
DGSVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWE
GNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDGD
NDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKG
SGYSLKATTMMIRPAD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1z3s Chain A Residue 497 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1z3s Structure of the angiopoietin-2 receptor binding domain and identification of surfaces involved in Tie2 recognition.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		D429 D431 C433 C435
Binding residue
(residue number reindexed from 1)		D150 D152 C154 C156
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1z3s, PDBe:1z3s, PDBj:1z3s
PDBsum1z3s
PubMed15893672
UniProtO15123|ANGP2_HUMAN Angiopoietin-2 (Gene Name=ANGPT2)

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