Structure of PDB 1z0a Chain A Binding Site BS01

Receptor Information
>1z0a Chain A (length=166) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQDLTIGVEFGARMITIDGKQ
IKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDA
RQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTAS
NVEEAFINTAKEIYEK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1z0a Chain A Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1z0a Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Resolution2.12 Å
Binding residue
(original residue number in PDB)		S20 D61
Binding residue
(residue number reindexed from 1)		S19 D57
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Q65
Catalytic site (residue number reindexed from 1) Q61
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:1z0a, PDBe:1z0a, PDBj:1z0a
PDBsum1z0a
PubMed16034420
UniProtP61019|RAB2A_HUMAN Ras-related protein Rab-2A (Gene Name=RAB2A)

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