Structure of PDB 1yzq Chain A Binding Site BS01

Receptor Information
>1yzq Chain A (length=164) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIR
LQLWDTAGQERFRSLIPSYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRT
ERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNV
KQLFRRVAAALPGM
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1yzq Chain A Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1yzq Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Resolution1.78 Å
Binding residue
(original residue number in PDB)		T27 T45
Binding residue
(residue number reindexed from 1)		T14 T32
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Q72
Catalytic site (residue number reindexed from 1) Q59
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:1yzq, PDBe:1yzq, PDBj:1yzq
PDBsum1yzq
PubMed16034420
UniProtP20340|RAB6A_HUMAN Ras-related protein Rab-6A (Gene Name=RAB6A)

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