Structure of PDB 1yye Chain A Binding Site BS01
Receptor Information
>1yye Chain A (length=228) Species:
9606
(Homo sapiens) [
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LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISW
AKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVL
DRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMDS
SRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKG
MEHLLNMKCKNVVPVYDLLLEMLNAHVL
Ligand information
>1yye Chain C (length=10) [
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HKLVQLLTTT
Receptor-Ligand Complex Structure
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PDB
1yye
ERbeta ligands. 3. Exploiting two binding orientations of the 2-phenylnaphthalene scaffold to achieve ERbeta selectivity
Resolution
2.03 Å
Binding residue
(original residue number in PDB)
I310 K314 D489 E493
Binding residue
(residue number reindexed from 1)
I48 K52 D217 E221
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1yye
,
PDBe:1yye
,
PDBj:1yye
PDBsum
1yye
PubMed
15943471
UniProt
Q92731
|ESR2_HUMAN Estrogen receptor beta (Gene Name=ESR2)
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