Structure of PDB 1ytj Chain A Binding Site BS01

Receptor Information
>1ytj Chain A (length=99) Species: 11723 (Simian immunodeficiency virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQFHLWKRPVVTAHIEGQPVEVLLDTGADDSIVTGIELGPHYTPKIVGGI
GGFINTKEYKNVEVEVLGKRIKGTIMTGDTPINIFGRNLLTALGMSLNF
Ligand information
Receptor-Ligand Complex Structure
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PDB1ytj Three-dimensional structures of HIV-1 and SIV protease product complexes.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D25 G27 A28 D29 D30 V47 G48
Binding residue
(residue number reindexed from 1)		D25 G27 A28 D29 D30 V47 G48
Enzymatic activity
Catalytic site (original residue number in PDB) D25 T26 G27
Catalytic site (residue number reindexed from 1) D25 T26 G27
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1ytj, PDBe:1ytj, PDBj:1ytj
PDBsum1ytj
PubMed8841139
UniProtP05896|POL_SIVM1 Gag-Pol polyprotein (Gene Name=gag-pol)

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