Structure of PDB 1yti Chain A Binding Site BS01

Receptor Information
>1yti Chain A (length=99) Species: 11723 (Simian immunodeficiency virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQFHLWKRPVVTAHIEGQPVEVLLDTGADDSIVTGIELGPHYTPKIVGGI
GGFINTKEYKNVEVEVLGKRIKGTIMTGDTPINIFGRNLLTALGMSLNF
Ligand information
Receptor-Ligand Complex Structure
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PDB1yti Three-dimensional structures of HIV-1 and SIV protease product complexes.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		G27 D29 D30 K45 V47 G48 M76
Binding residue
(residue number reindexed from 1)		G27 D29 D30 K45 V47 G48 M76
Enzymatic activity
Catalytic site (original residue number in PDB) D25 T26 G27
Catalytic site (residue number reindexed from 1) D25 T26 G27
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1yti, PDBe:1yti, PDBj:1yti
PDBsum1yti
PubMed8841139
UniProtP05896|POL_SIVM1 Gag-Pol polyprotein (Gene Name=gag-pol)

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