Structure of PDB 1yt8 Chain A Binding Site BS01

Receptor Information

>1yt8 Chain A (length=525) Species: 287 (Pseudomonas aeruginosa)

IAVRTFHDIRAALLARRELALLDVREEDPFAQAHPLFAANLPLSRLELEI
HARVPRRDTPITVYDDGEGLAPVAAQRLHDLGYSDVALLDGGLSGWRNAG
GELFRDVNVPSKAFGELVEAERHTPSLAAEEVQALLDARAEAVILDARRF
DEYQTMSIPGGISVPGAELVLRVAELAPDPRTRVIVNCAGRTRSIIGTQS
LLNAGIPNPVAALRNGTIGWTLAGQQLEHGQTRRFGAISQDTRKAAAQRA
RAVADRAGVERLDLAGLAQWQDEHDRTTYLLDVRTPEEYEAGHLPGSRST
PGGQLVQETDHVASVRGARLVLVDDDGVRANMSASWLAQMGWQVAVLDGL
SEADFSERGAWSAPLPRQPRADTIDPTTLADWLGEPGTRVLDFTASANYA
KRHIPGAAWVLRSQLKQALERLGTAERYVLTCGSSLLARFAVAEVQALSG
KPVFLLDGGTSAWVAAGLPTEDGESLLASPRIDRYRRPYEGTDNPREAMQ
GYLDWEFGLVEQLGRDGTHGFFVIE

Ligand information

• Ligand ID: SO3
• InChI: InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-2
• InChIKey: LSNNMFCWUKXFEE-UHFFFAOYSA-L
• SMILES:
  CACTVS 3.341: [O-][S]([O-])=O
  OpenEye OEToolkits 1.5.0: [O-]S(=O)[O-]
  ACDLabs 10.04: [O-]S([O-])=O
• Formula: O3 S
• Name: SULFITE ION
• PDB chain: 1yt8 Chain A Residue 540

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1yt8 Crystal Structure of Thiosulfate sulfurtransferase from Pseudomonas aeruginosa
• Resolution: 1.9 Å
• Binding residue (original residue number in PDB): C193 A194 G195 R196 T197 R198
• Binding residue (residue number reindexed from 1): C188 A189 G190 R191 T192 R193
• Annotation score: 5

Enzymatic activity

• Enzyme Commision number: 2.8.1.1: thiosulfate sulfurtransferase.

Gene Ontology

Molecular Function

• GO:0004792 thiosulfate sulfurtransferase activity

External links

• PDB: RCSB:1yt8, PDBe:1yt8, PDBj:1yt8
• PDBsum: 1yt8
• UniProt: Q9I0N4