Structure of PDB 1yrk Chain A Binding Site BS01
Receptor Information
>1yrk Chain A (length=126) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
GSHMAPFLRIAFNSYELGSLQAEDEANQPFCAVKMKEALSTERGKTLVQK
KPTMYPEWKSTFDAHIYEGRVIQIVLMRAAEEPVSEVTVGVSVLAERCKK
NNGKAEFWLDLQPQAKVLMSVQYFLE
Ligand information
>1yrk Chain B (length=13) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
MALYSIYQPYVFA
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
1yrk
The C2 domain of PKCdelta is a phosphotyrosine binding domain.
Resolution
1.7 Å
Binding residue
(original residue number in PDB)
F4 R6 K48 P49 M51 Y52 D60 A61 H62 R67 F121 L122 E123
Binding residue
(residue number reindexed from 1)
F7 R9 K51 P52 M54 Y55 D63 A64 H65 R70 F124 L125 E126
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
2.7.11.13
: protein kinase C.
External links
PDB
RCSB:1yrk
,
PDBe:1yrk
,
PDBj:1yrk
PDBsum
1yrk
PubMed
15851022
UniProt
Q05655
|KPCD_HUMAN Protein kinase C delta type (Gene Name=PRKCD)
[
Back to BioLiP
]
