Structure of PDB 1yow Chain A Binding Site BS01

Receptor Information
>1yow Chain A (length=230) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNVPELMLQLLQLEPDEDQVRARILGCLQEPAAFGLLCRMADQTFISIVD
WARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTG
QEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFS
LDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRA
LSMQAKEYLYHKHLGNEMPRNNLLIEMLQA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1yow Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1
Resolution3.0 Å
Binding residue
(original residue number in PDB)		Q294 M295 E454 M455
Binding residue
(residue number reindexed from 1)		Q66 M67 E226 M227
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity

View graph for
Molecular Function
External links
PDB RCSB:1yow, PDBe:1yow, PDBj:1yow
PDBsum1yow
PubMed15707893
UniProtQ13285|STF1_HUMAN Steroidogenic factor 1 (Gene Name=NR5A1)

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