Structure of PDB 1yop Chain A Binding Site BS01

Receptor Information
>1yop Chain A (length=83) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVSTYDEIEIEDMTFEPENQMFTYPCPCGDRFQIYLDDMFEGEKVAVCPS
CSLMIDVVFDKEDLAEYYEEAGIHPPEPIAAAA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1yop Chain A Residue 84 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1yop Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.
ResolutionN/A
Binding residue
(original residue number in PDB)		C26 C28 C48 C51
Binding residue
(residue number reindexed from 1)		C26 C28 C48 C51
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0008198 ferrous iron binding
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors
GO:0034986 iron chaperone activity
GO:0046872 metal ion binding
GO:0090560 2-(3-amino-3-carboxypropyl)histidine synthase activity
Biological Process
GO:0002098 tRNA wobble uridine modification
GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation
GO:0008033 tRNA processing
GO:0017183 protein histidyl modification to diphthamide
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1yop, PDBe:1yop, PDBj:1yop
PDBsum1yop
PubMed15952786
UniProtQ3E840|DPH3_YEAST Diphthamide biosynthesis protein 3 (Gene Name=KTI11)

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