Structure of PDB 1ymm Chain A Binding Site BS01

Receptor Information
>1ymm Chain A (length=182) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRF
ASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELRE
PNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYL
PFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ymm Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
Q9 E11 R50 F51 A52 S53 F54 G58 N62 N69 I72
Binding residue
(residue number reindexed from 1)
Q8 E10 R49 F50 A51 S52 F53 G57 N61 N68 I71
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:1ymm, PDBe:1ymm, PDBj:1ymm
PDBsum1ymm
PubMed15821740
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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