Structure of PDB 1yk1 Chain A Binding Site BS01

Receptor Information
>1yk1 Chain A (length=394) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALPPQKIEVLVLLPQDDSYLFSLTRVRPAIEYALRSVEGLLPPGTRFQVA
YEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDL
PMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAAL
VYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQ
ASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSW
KRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMED
YVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAG
QVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRP
Ligand information
>1yk1 Chain E (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GCFGRKMDRISSSSGLGCKVL
Receptor-Ligand Complex Structure
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PDB1yk1 Structural determinants of natriuretic peptide receptor specificity and degeneracy.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		E92 Y93 A96 R100 G118 F119 E125 Y169 E173 H176
Binding residue
(residue number reindexed from 1)		E85 Y86 A89 R93 G111 F112 E118 Y162 E166 H169
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:1yk1, PDBe:1yk1, PDBj:1yk1
PDBsum1yk1
PubMed16870210
UniProtP17342|ANPRC_HUMAN Atrial natriuretic peptide receptor 3 (Gene Name=NPR3)

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