Structure of PDB 1yjm Chain A Binding Site BS01

Receptor Information

>1yjm Chain A (length=107) Species: 10090 (Mus musculus)

LGSRGRLWLQSPTGGPPPIFLPSDGQALVLGRGPLTQVTDRKCSRNQVEL
IADPESRTVAVKQLGVNPSTVGVHELKPGLSGSLSLGDVLYLVNGLYPLT
LRWEELS

Ligand information

>1yjm Chain E (length=7)

YDESTDE

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1yjm The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase.
• Resolution: 2.2 Å
• Binding residue (original residue number in PDB): R35 G36 V41 R44 S47 R48 V69
• Binding residue (residue number reindexed from 1): R32 G33 V38 R41 S44 R45 V66

Enzymatic activity

• Enzyme Commision number: 2.7.1.78: polynucleotide 5'-hydroxyl-kinase.
  3.1.3.32: polynucleotide 3'-phosphatase.

External links

• PDB: RCSB:1yjm, PDBe:1yjm, PDBj:1yjm
• PDBsum: 1yjm
• PubMed: 15749016
• UniProt: Q9JLV6|PNKP_MOUSE Bifunctional polynucleotide phosphatase/kinase (Gene Name=Pnkp)