Structure of PDB 1y6g Chain A Binding Site BS01

Receptor Information
>1y6g Chain A (length=392) Species: 10665 (Tequatrovirus T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGSMRICIFMARGLEGCGVTKFSLEQRDWFIKNGHEVTLVYAKDKSFTRT
SSHDHKSFSIPVILAKEYDKALKLVNDCDILIINSVPATSVQEATINNYK
KLLDNIKPSIRVVVYQHDHSVLSLRRNLGLEETVRRADVIFSHSDNGDFN
KVLMKEWYPAPTVYNFQPPMDIVKVRSTYWKDVSEINMNINRWIGRTTTW
KGFYQMFDFHEKFLKPAGKSTVMEGLERSPAFIAIKEKGIPYEYYGNREI
DKMNLAPNQPAQILDCYINSEMLERMSKSGFGYQLSKLNQKYLQRSLEYT
HLELGACGTIPVFWKSTGENLKFRVDNTPLTSHDSGIIWFDENDMESTFE
RIKELSSDRALYDREREKAYEFLYQHQDSSFCFKEQFDIITK
Ligand information
Receptor-Ligand Complex Structure
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PDB1y6g Structural evidence of a passive base-flipping mechanism for AGT, an unusual GT-B glycosyltransferase.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		T1206 T1207 W1208 E1235 R1236 S1237 A1239
Binding residue
(residue number reindexed from 1)		T198 T199 W200 E227 R228 S229 A231
Enzymatic activity
Enzyme Commision number 2.4.1.26: DNA alpha-glucosyltransferase.
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0033820 DNA alpha-glucosyltransferase activity
Biological Process
GO:0006304 DNA modification
GO:0019049 virus-mediated perturbation of host defense response
GO:0039504 symbiont-mediated suppression of host adaptive immune response
GO:0098672 symbiont-mediated suppression of host CRISPR-cas system
GO:0099018 symbiont-mediated evasion of host restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1y6g, PDBe:1y6g, PDBj:1y6g
PDBsum1y6g
PubMed16081100
UniProtP04519|GSTA_BPT4 DNA alpha-glucosyltransferase (Gene Name=agt)

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