Structure of PDB 1xzw Chain A Binding Site BS01

Receptor Information

>1xzw Chain A (length=424) Species: 4120 (Ipomoea batatas) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LPNAEDVDMPWDSDVFAVPSGYNAPQQVHITQGDYEGRGVIISWTTPYDK
AGANKVFYWSENSKSQKRAMGTVVTYKYYNYTSAFIHHCTIKDLEYDTKY
YYRLGFGDAKRQFWFVTPPKPGPDVPYVFGLIGDIGQTHDSNTTLTHYEQ
NSAKGQAVLFMGDLSYSNRWPNHDNNRWDTWGRFSERSVAYQPWIWTAGN
HEIDYAPDIGEYQPFVPFTNRYPTPHEASGSGDPLWYAIKRASAHIIVLS
SYSGFVKYSPQYKWFTSELEKVNRSETPWLIVLVHAPLYNSYEAHYMEGE
AMRAIFEPYFVYYKVDIVFSGHVHSYERSERVSNVAYNIVNAKCTPVSDE
SAPVYITIGDGGNSEGLASEMTQPQPSYSAFREASFGHGIFDIKNRTHAH
FSWHRNQDGASVEADSLWLLNRYW

Ligand information

Ligand ID

InChI

InChI=1S/Fe/q+3

InChIKey

VTLYFUHAOXGGBS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Fe+3]

Formula

Name

FE (III) ION

PDB chain

1xzw Chain A Residue 429 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1xzw Phosphate forms an unusual tripodal complex with the Fe-Mn center of sweet potato purple acid phosphatase
Resolution	2.5 Å
Binding residue (original residue number in PDB)	D134 D163 Y166 H324
Binding residue (residue number reindexed from 1)	D134 D163 Y166 H324
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.1.3.2: acid phosphatase.

Gene Ontology

	Molecular Function
GO:0003993	acid phosphatase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

	Cellular Component
GO:0005576	extracellular region

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Molecular Function

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Cellular Component

External links

PDB	RCSB:1xzw, PDBe:1xzw, PDBj:1xzw
PDBsum	1xzw
PubMed	15625111
UniProt	Q9SE00\|PPAF1_IPOBA Purple acid phosphatase 1 (Gene Name=PAP1)

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