Structure of PDB 1xwy Chain A Binding Site BS01

Receptor Information
>1xwy Chain A (length=260) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MFDIGVNLTSSQFAKDRDDVVACAFDAGVNGLLITGTNLRESQQAQKLAR
QYSSCWSTAGVHPHDSSQWQAATEEAIIELAAQPEVVAIGECGLDFNRNF
STPEEQERAFVAQLRIAADLNMPVFMHCRDAHERFMTLLEPWLDKLPGAV
LHCFTGTREEMQACVAHGIYIGITGWVCDERRGLELRELLPLIPAEKLLI
ETDAPYLLPRDLTPKPSSRRNEPAHLPHILQRIAHWRGEDAAWLAATTDA
NVKTLFGIAF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1xwy Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1xwy Crystal structure of tatD DNase from Escherichia coli at 2.0 A resolution
Resolution2.0 Å
Binding residue
(original residue number in PDB)		H152 C153 E201
Binding residue
(residue number reindexed from 1)		H152 C153 E201
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.11.-
3.1.13.-
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0000287 magnesium ion binding
GO:0004527 exonuclease activity
GO:0004536 DNA nuclease activity
GO:0008310 single-stranded DNA 3'-5' DNA exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0046872 metal ion binding
Biological Process
GO:0006259 DNA metabolic process
GO:0042542 response to hydrogen peroxide
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1xwy, PDBe:1xwy, PDBj:1xwy
PDBsum1xwy
PubMed
UniProtP27859|TATD_ECOLI 3'-5' ssDNA/RNA exonuclease TatD (Gene Name=tatD)

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