Structure of PDB 1xr8 Chain A Binding Site BS01

Receptor Information
>1xr8 Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAP
WIEQEGPEYWDRETQISKTNTQTYRESLRNLRGYYNQSEAGSHTLQRMYG
CDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
REAEQWRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>1xr8 Chain C (length=9) Species: 10377 (Human herpesvirus 4 strain B95-8) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LEKARGSTY
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1xr8 Crystal structures of two peptide-HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype
Resolution2.3 Å
Binding residue
(original residue number in PDB)
Y7 Y9 M45 R62 E63 I66 E76 S77 Y84 R97 Y99 S116 T143 K146 W147 W156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y9 M45 R62 E63 I66 E76 S77 Y84 R97 Y99 S116 T143 K146 W147 W156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1xr8, PDBe:1xr8, PDBj:1xr8
PDBsum1xr8
PubMed17057332
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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