Structure of PDB 1xow Chain A Binding Site BS01
Receptor Information
>1xow Chain A (length=243) Species:
9606
(Homo sapiens) [
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PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIATSCSRRFYQLTKLLDSVQPIARELHQF
TFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
Ligand information
>1xow Chain B (length=10) Species:
9606
(Homo sapiens) [
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GAFQNLFQSV
Receptor-Ligand Complex Structure
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PDB
1xow
Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
V716 K720 Q733 M734 I737 Q738 M894 E897
Binding residue
(residue number reindexed from 1)
V46 K50 Q63 M64 I67 Q68 M218 E221
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1xow
,
PDBe:1xow
,
PDBj:1xow
PDBsum
1xow
PubMed
15525515
UniProt
P10275
|ANDR_HUMAN Androgen receptor (Gene Name=AR)
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