Structure of PDB 1xns Chain A Binding Site BS01

Receptor Information
>1xns Chain A (length=322) Species: 10678 (Punavirus P1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEPE
DVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRR
IRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAYN
TLLRIAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGVEKALSLGVTK
LVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATH
RLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVN
IVMNYIRNLDSETGAMVRLLED
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1xns Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		F37 S38 H40 T41 I174 A175 K244 N245 R259 E262 K276 R282 Y283 S287 G288 H289
Binding residue
(residue number reindexed from 1)		F18 S19 H21 T22 I155 A156 K225 N226 R240 E243 K257 R263 Y264 S268 G269 H270
Binding affinityPDBbind-CN: Kd=1.3uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1xns, PDBe:1xns, PDBj:1xns
PDBsum1xns
PubMed15591069
UniProtP06956|RECR_BPP1 Recombinase cre (Gene Name=cre)

[Back to BioLiP]