Structure of PDB 1xgs Chain A Binding Site BS01
Receptor Information
>1xgs Chain A (length=295) Species:
2261
(Pyrococcus furiosus) [
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MDTEKLMKAGEIAKKVREKAIKLARPGMLLLELAESIEKMIMELGGKPAF
PVNLSINEIAAHYTPYKGDTTVLKEGDYLKIDVGVHIDGFIADTAVTVRV
GMEEDELMEAAKEALNAAISVARAGVEIKELGKAIENEIRKRGFKPIVNL
SGHKIERYKLHAGISIPNIYRPHDNYVLKEGDVFAIEPFATIGAGQVIEV
PPTLIYMYVRDVPVRVAQARFLLAKIKREYGTLPFAYRWLQNDMPEGQLK
LALKTLEKAGAIYGYPVLKEIRNGIVAQFEHTIIVEKDSVIVTTE
Ligand information
Ligand ID
CO
InChI
InChI=1S/Co/q+2
InChIKey
XLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Co+2]
CACTVS 3.341
[Co++]
Formula
Co
Name
COBALT (II) ION
ChEMBL
DrugBank
DB14205
ZINC
PDB chain
1xgs Chain A Residue 296 [
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Receptor-Ligand Complex Structure
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PDB
1xgs
Crystal structure of methionine aminopeptidase from hyperthermophile, Pyrococcus furiosus.
Resolution
1.75 Å
Binding residue
(original residue number in PDB)
D93 H153 E187 E280
Binding residue
(residue number reindexed from 1)
D93 H153 E187 E280
Annotation score
3
Enzymatic activity
Catalytic site (original residue number in PDB)
D82 D93 H153 H161 E187 E280
Catalytic site (residue number reindexed from 1)
D82 D93 H153 H161 E187 E280
Enzyme Commision number
3.4.11.18
: methionyl aminopeptidase.
Gene Ontology
Molecular Function
GO:0004177
aminopeptidase activity
GO:0004239
initiator methionyl aminopeptidase activity
GO:0008235
metalloexopeptidase activity
GO:0046872
metal ion binding
GO:0070006
metalloaminopeptidase activity
Biological Process
GO:0006508
proteolysis
Cellular Component
GO:0005737
cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:1xgs
,
PDBe:1xgs
,
PDBj:1xgs
PDBsum
1xgs
PubMed
9811545
UniProt
P56218
|MAP2_PYRFU Methionine aminopeptidase (Gene Name=map)
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