Structure of PDB 1xdk Chain A Binding Site BS01

Receptor Information
>1xdk Chain A (length=217) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANEDMPVEKILEAELAVEPPNDPVTNICQAADKQLFTLVEWAKRIPHFSE
LPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAG
VGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEA
LREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKL
IGDTPIDTFLMEMLEAP
Ligand information
Receptor-Ligand Complex Structure
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PDB1xdk CHARACTERIZATION OF THE INTERACTION BETWEEN RAR/RXR HETERODIMERS AND TRANSCRIPTIONAL COACTIVATORS THROUGH STRUCTURAL AND FLUORESCENCE ANISOTROPY STUDIES
Resolution2.9 Å
Binding residue
(original residue number in PDB)		V285 K289 L299 Q302 V303 R307 F455 E458 P463
Binding residue
(residue number reindexed from 1)		V39 K43 L53 Q56 V57 R61 F209 E212 P217
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1xdk, PDBe:1xdk, PDBj:1xdk
PDBsum1xdk
PubMed15528208
UniProtP28700|RXRA_MOUSE Retinoic acid receptor RXR-alpha (Gene Name=Rxra)

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