Structure of PDB 1x7e Chain A Binding Site BS01
Receptor Information
>1x7e Chain A (length=238) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPVKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLIL
SHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRL
Ligand information
>1x7e Chain C (length=11) [
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HKILHRLLQDS
Receptor-Ligand Complex Structure
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PDB
1x7e
Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 E76 L228 E231
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1x7e
,
PDBe:1x7e
,
PDBj:1x7e
PDBsum
1x7e
PubMed
15548008
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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