Structure of PDB 1wsu Chain A Binding Site BS01

Receptor Information
>1wsu Chain A (length=124) Species: 1525 (Moorella thermoacetica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSETQKKLLKDLEDKYRVSRWQPPSFKEVAGSFNLDPSELEELLHYLVRE
GVLVKINDEFYWHRQALGEAREVIKNLASTGPFGLAEARDALGSSRKYVL
PLLEYLDQVKFTRRVGDKRVVVGN
Ligand information
>1wsu Chain E (length=22) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcguugccggucggcaacgcc
<<<<<<<<<<..>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB1wsu Structural basis for mRNA recognition by elongation factor SelB
Resolution2.3 Å
Binding residue
(original residue number in PDB)
R599 S605 R606 K607 L610 R624 R629
Binding residue
(residue number reindexed from 1)
R89 S95 R96 K97 L100 R114 R119
Binding affinityPDBbind-CN: Kd=0.2nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0005525 GTP binding
Biological Process
GO:0001514 selenocysteine incorporation
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1wsu, PDBe:1wsu, PDBj:1wsu
PDBsum1wsu
PubMed15665870
UniProtQ46455|SELB_MOOTH Selenocysteine-specific elongation factor (Gene Name=selB)

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