Structure of PDB 1wrn Chain A Binding Site BS01

Receptor Information
>1wrn Chain A (length=146) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLHKERRIGRLSVLLLLNEAESTQVEELERDGWKVCLGKVGSMDAHKVIA
AIETASKKSGVIQSEGYRESHALYHATMEALHGVTRGEMLLGSLLRTVGL
RFAVLRGNPYESEAEGDWIAVSLYGTIGAPIKGLEHETFGVGINHI
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain1wrn Chain A Residue 4002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1wrn Characterization of the metal ion binding site in the anti-terminator protein, HutP, of Bacillus subtilis
Resolution2.3 Å
Binding residue
(original residue number in PDB)		H73 H77
Binding residue
(residue number reindexed from 1)		H71 H75
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
Biological Process
GO:0006547 L-histidine metabolic process
GO:0010628 positive regulation of gene expression

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Molecular Function
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Biological Process
External links
PDB RCSB:1wrn, PDBe:1wrn, PDBj:1wrn
PDBsum1wrn
PubMed16192572
UniProtP10943|HUTP_BACSU Hut operon positive regulatory protein (Gene Name=hutP)

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