Structure of PDB 1wni Chain A Binding Site BS01

Receptor Information
>1wni Chain A (length=198) Species: 88087 (Protobothrops flavoviridis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FPQRYIELAIVVDHGMYKKYNQNSDKIKVRVHQMVNHINEMYRPLNIAIS
LNRLQIWSKKDLITVKSASNVTLESFGNWRETVLLKQQNNDCAHLLTATN
LNDNTIGLAYKKGMCNPKLSVGLVQDYSPNVFMVAVTMTHELGHNLGMEH
DDKDKCKCEACIMSDVISDKPSKLFSDCSKNDYQTFLTKYNPQCILNA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1wni Chain A Residue 999 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1wni Crystal structure of H2-proteinase from the venom of Trimeresurus flavoviridis.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		H142 H146 H152
Binding residue
(residue number reindexed from 1)		H140 H144 H150
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.24.53: trimerelysin II.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1wni, PDBe:1wni, PDBj:1wni
PDBsum1wni
PubMed8907175
UniProtP20165|VM1T2_PROFL Snake venom metalloproteinase trimerelysin-2

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