Structure of PDB 1wf3 Chain A Binding Site BS01

Receptor Information

>1wf3 Chain A (length=296) Species: 300852 (Thermus thermophilus HB8)

EKTYSGFVAIVGKPNVGKSTLLNNLLGVKVAPISPRPQTTRKRLRGILTE
GRRQIVFVDTPGLHKPMDALGEFMDQEVYEALADVNAVVWVVDLRHPPTP
EDELVARALKPLVGKVPILLVGNKLDAAKYPEEAMKAYHELLPEAEPRML
SALDERQVAELKADLLALMPEGPFFYPEDYAKSDQTFGEWVAEILREEAM
KRLWHEVPYAVATKVEEVAERENGVLYIKAILYVERPSQKAIVIGEGGRK
IKEIGQATRKQLEALLGKKVYLDLEVKVYPDWRKDPEALRELGYRS

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 1wf3 Chain A Residue 401

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1wf3 Crystal structure of GTP-binding protein TT1341 from Thermus thermophilus HB8
• Resolution: 1.88 Å
• Binding residue (original residue number in PDB): S21 T42
• Binding residue (residue number reindexed from 1): S19 T40
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003924 GTPase activity
• GO:0005525 GTP binding
• GO:0019843 rRNA binding
• GO:0043024 ribosomal small subunit binding
• GO:0070181 small ribosomal subunit rRNA binding

Biological Process

• GO:0000028 ribosomal small subunit assembly
• GO:0042254 ribosome biogenesis
• GO:0042274 ribosomal small subunit biogenesis

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005886 plasma membrane

External links

• PDB: RCSB:1wf3, PDBe:1wf3, PDBj:1wf3
• PDBsum: 1wf3
• UniProt: Q5SM23|ERA_THET8 GTPase Era (Gene Name=era)