Structure of PDB 1wcz Chain A Binding Site BS01

Receptor Information
>1wcz Chain A (length=215) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VILPNNDRHQITDTTNGHYAPVTYIQVEATGTFIASGVVVGKDTLLTNKH
VVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSP
NEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKIT
YLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFINEN
VRNFLKQNIEDINFA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1wcz Chain A Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1wcz Crystal structure of an alkaline form of v8 protease from Staphylococcus aureus
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D7 H9 K147
Binding residue
(residue number reindexed from 1)		D7 H9 K146
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.19: glutamyl endopeptidase.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1wcz, PDBe:1wcz, PDBj:1wcz
PDBsum1wcz
PubMed
UniProtP0C1U8|SSPA_STAAU Glutamyl endopeptidase (Gene Name=sspA)

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