Structure of PDB 1w9i Chain A Binding Site BS01

Receptor Information
>1w9i Chain A (length=702) Species: 44689 (Dictyostelium discoideum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPIHDRTSDYHKYLKVKQGDKRYIWYNPDPKERDSYECGEIVSETSDSFT
FKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPAVFHNLRVRYN
QDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEVAPHIFAISDV
AYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAGRGVLEQQILQ
ANPILEAFGNAKTTRNNNSSRFGKFIEIQFNSAGFISGASIQSYLLEKSR
VVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESFNYLNQSGCVDIKG
VSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIKFEKGAGEGA
VLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQHLNVEKSSSS
RDALVKALYGRLFLWLVKKINNVLCQERKAYFIGVLDIYGFEIFKVNSFE
QLCINYTNEKLQQFFNHHMFKLEQEEYLKEKINWTFIDFGLDSQATIDLI
DGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEPRFSKTE
FGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDNVVTKLFNDPNI
ASRAKKGANFITVAAQYKEQLASLMATLETTNPHFVRCIIPNNKQLPAKL
EDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADQFRFGITKIFFRAGQLA
RI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1w9i Chain A Residue 1755 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1w9i Structure-Function Analysis of Myosin II Backdoor Mutants
Resolution1.75 Å
Binding residue
(original residue number in PDB)		T186 S237 I754
Binding residue
(residue number reindexed from 1)		T175 S220 I702
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) S181 G182 T186 N233 S236 S237 G457 E459
Catalytic site (residue number reindexed from 1) S170 G171 T175 N216 S219 S220 G440 E442
Enzyme Commision number 3.6.4.1: Transferred entry: 5.6.1.8.
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:1w9i, PDBe:1w9i, PDBj:1w9i
PDBsum1w9i
PubMed
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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