Structure of PDB 1w0u Chain A Binding Site BS01

Receptor Information
>1w0u Chain A (length=55) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMK
RLGMN
Ligand information
Receptor-Ligand Complex Structure
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PDB1w0u How the Human Telomeric Proteins Trf1 and Trf2 Recognize Telomeric DNA: A View from High-Resolution Crystal Structures
Resolution1.8 Å
Binding residue
(original residue number in PDB)
K447 G468 W470 K488 R492
Binding residue
(residue number reindexed from 1)
K2 G23 W25 K43 R47
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0042162 telomeric DNA binding
Biological Process
GO:0000723 telomere maintenance
GO:0031848 protection from non-homologous end joining at telomere
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:1w0u, PDBe:1w0u, PDBj:1w0u
PDBsum1w0u
PubMed15608617
UniProtQ15554|TERF2_HUMAN Telomeric repeat-binding factor 2 (Gene Name=TERF2)

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