Structure of PDB 1v71 Chain A Binding Site BS01

Receptor Information
>1v71 Chain A (length=318) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLPTYDDVASASERIKKFANKTPVLTSSTVNKEFVAEVFFKCENFQKMGA
FKFRGALNALSQLNEAQRKAGVLTFSSGNHAQAIALSAKILGIPAKIIMP
LDAPEAKVAATKGYGGQVIMYDRYKDDREKMAKEISEREGLTIIPPYDHP
HVLAGQGTAAKELFEEVGPLDALFVCLGGGGLLSGSALAARHFAPNCEVY
GVEPEAGNDGQQSFRKGSIVHIDTPKTIADGAQTQHLGNYTFSIIKEKVD
DILTVSDEELIDCLKFYAARMKIVVEPTGCLSFAAARAMKEKLKNKRIGI
IISGGNVDIERYAHFLSQ
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1v71 Chain A Residue 360 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1v71 Crystal Structure of S.pombe Serine Racemase
Resolution1.7 Å
Binding residue
(original residue number in PDB)		E208 G212 D214
Binding residue
(residue number reindexed from 1)		E203 G207 D209
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) K57 S82 E208 G212 D214 G236 I307 S308
Catalytic site (residue number reindexed from 1) K52 S77 E203 G207 D209 G231 I302 S303
Enzyme Commision number 4.3.1.17: L-serine ammonia-lyase.
4.3.1.18: D-serine ammonia-lyase.
5.1.1.18: serine racemase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0003941 L-serine ammonia-lyase activity
GO:0005524 ATP binding
GO:0008721 D-serine ammonia-lyase activity
GO:0016829 lyase activity
GO:0016853 isomerase activity
GO:0018114 threonine racemase activity
GO:0030170 pyridoxal phosphate binding
GO:0030378 serine racemase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006563 L-serine metabolic process
GO:0070178 D-serine metabolic process
Cellular Component
GO:0005575 cellular_component

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Biological Process
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Cellular Component
External links
PDB RCSB:1v71, PDBe:1v71, PDBj:1v71
PDBsum1v71
PubMed
UniProtO59791|SRR_SCHPO Serine racemase (Gene Name=sry1)

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